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SRP5091

Sigma-Aldrich

TGFβR1 (80-end), active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

AAT5, ACVRLK4, ALK-5, LDS1A, LSD2A, SKR4, TGFR-1

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
Pricing and availability is not currently available.

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

2.5-3.5 nmol/min·mg

mol wt

~66 kDa

NCBI accession no.

BC071181

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... TGFBR1(7046)

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Anti-Serotonin Receptor 1B Antibody, clone 1C2.1 clone 1C2.1, from mouse

MABN1539

Anti-Serotonin Receptor 1B Antibody, clone 1C2.1

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified antibody

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

UniProt accession no.

P46098

UniProt accession no.

P28222

UniProt accession no.

P47898

UniProt accession no.

P28222

species reactivity

human

species reactivity

human, mouse, rat

species reactivity

human

species reactivity

human, rat, mouse

shipped in

ambient

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

TGFβR1 or transforming growth factor, beta-receptor 1 is a member of the TGFβ receptor subfamily and is a ser/thr protein kinase that forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Mutations in TGFβR1gene have been associated with Marfan syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. TGFβR1-dependent signaling is required for angiogenesis but not for the development of hematopoietic progenitor cells and functional hematopoiesis.

Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Lot/Batch Number
    N270-2

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