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SRP5291

Sigma-Aldrich

PLK3, active, GST tagged human

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

CNK, FNK, PRK

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32
Pricing and availability is not currently available.

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO®

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

1.8-2.6 nmol/min·mg

mol wt

~60 kDa

NCBI accession no.

NM_004073

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PLK3(1263)

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PLK3, active, GST tagged human PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

SRP5291

PLK3, active, GST tagged human

PLK3 Polo Box Domain human recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

SRP0361

PLK3 Polo Box Domain human

PLK4, active, GST tagged human PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

SRP5315

PLK4, active, GST tagged human

PLK1, active, His tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

P0060

PLK1, active, His tagged human

Gene Information

human ... PLK3(1263)

Gene Information

human ... PLK3(1263)

Gene Information

human ... PLK4(10733)

Gene Information

human ... PLK1(5347)

assay

≥70% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

specific activity

1.8-2.6 nmol/min·mg

specific activity

-

specific activity

4.5-6.7 nmol/min·mg

specific activity

14-20 nmol/min·mg

form

buffered aqueous glycerol solution

form

aqueous solution

form

buffered aqueous glycerol solution

form

buffered aqueous glycerol solution

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

mol wt

~60 kDa

mol wt

80.5 kDa

mol wt

~140 kDa

mol wt

~70 kDa

General description

PLK3 or Polo-like kinase 3 is a cytokine-inducible kinase that is a member of the Polo family of serine/threonine protein kinases. PLK3 contains both a catalytic domain and a putative regulatory domain and plays an important role in the regulation of cell cycle progression and tumorigenesis. PLK3 is closely associated with centrosomes in several human cell lines and its localization is dependent on the integrity of microtubules. Hence, PLK3 is also involved in regulating microtubule dynamics and centrosomal function.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    I148-2

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