T1147

apo-Transferrin human

powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

• Synonym(s): Human transferrin, Siderophilin
• CAS Number: 11096-37-0
• EC Number: 234-318-8
• MDL number: MFCD00130536
• UNSPSC Code: 12352202
• NACRES: NA.75

Properties

• biological source: human plasma
• product line: BioReagent
• assay: ≥98% (agarose gel electrophoresis)
• form: powder
• mol wt: 76-81 kDa
• concentration: ~25 mM
• technique(s): cell culture | mammalian: suitable
• impurities: HIV and HBsAg, source material tested negative; ≤0.005% iron
• solubility: H₂O: 50 mg/mL
• UniProt accession no.: P02787
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TF(7018)

Description

Application

Apo-Transferrin human can be supplemented with iron or used to bind free iron present in media. It is also used to transport iron into mammalian cells.

Biochem/physiol Actions

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Human apo-transferrin is a high affinity transferrin that can be used with a wide range of cells types. Apo-transferrin can be loaded with iron prior to use or added directly to an iron containing medium.

Other Notes

Non-heme iron-transport protein.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3