T3766

Thymine 1-β-D-arabinofuranoside

≥99%

• Synonym(s): araT, 1-β-D-Arabinofuranosylthymine
• Empirical Formula (Hill Notation): C₁₀H₁₄N₂O₆
• CAS Number: 605-23-2
• Molecular Weight: 258.23
• EC Number: 210-083-7
• MDL number: MFCD00065474
• UNSPSC Code: 41106305
• PubChem Substance ID: 24900167
• NACRES: NA.51

Properties

• Quality Level: 200
• assay: ≥99%
• form: powder
• optical activity: [α]20/D 90°, c = 5 mg/mL in water
• solubility: 0.5 M HCl: 20 mg/mL, clear, colorless
• storage temp.: 2-8°C
• SMILES string: CC1=CN(C2OC(CO)C(O)C2O)C(=O)NC1=O
• InChI: 1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)
• InChI key: DWRXFEITVBNRMK-UHFFFAOYSA-N

Description

Application

1-β-D-Arabinofuranosylthymine (araT):

• maybe used as a substrate and inhibitor to study the specificity and kinetics of thymidine kinase(s), such as herpes simplex virus type 1 and 2 thymidine kinases, the HSV1-tk and, HSV2-tk gene products.
• is used to study the specificity and kinetics of various mitochondrial nucleoside kinases.
• has been used as an antiviral agent to study its efficacy on Cryptosporidium parvum in vitro.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)