V7264
Venlafaxine hydrochloride
≥98% (HPLC), powder
Synonym(s):
(+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C17H27NO2 · HCl
CAS Number:
Molecular Weight:
313.86
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
protect from light
color
white
solubility
H2O: >10 mg/mL
originator
Wyeth
SMILES string
Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
InChI
1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
InChI key
QYRYFNHXARDNFZ-UHFFFAOYSA-N
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Related Categories
1 of 4
This Item | PHR1736 | BP835 | Y0000587 |
|---|---|---|---|
| assay ≥98% (HPLC) | assay - | assay - | assay - |
| form powder | form - | form solid | form - |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| solubility H2O: >10 mg/mL | solubility - | solubility - | solubility - |
| storage condition desiccated, protect from light | storage condition - | storage condition - | storage condition - |
| originator Wyeth | originator - | originator - | originator - |
Biochem/physiol Actions
Venlafaxine is a dual serotonin-noradrenaline reuptake inhibitor that displays Ki values of 82 and 2480 nM respectively. It is a general class antidepressant.
Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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