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Astec® CHIROBIOTIC® T2 Chiral (5 μm) HPLC Columns

L × I.D. 10 cm × 2.1 mm, HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Pricing and availability is not currently available.

Product Name

Astec® CHIROBIOTIC® T2 Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 2.1 mm

material

stainless steel column

Quality Level

100

agency

suitable for USP L63

description

HPLC column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature
241 bar pressure (3500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

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Valco® Precision Sampling Syringe, Series A-2, Removable needle volume 1000 μL, bevel tip stainless steel needle (point style 2), needle L × O.D. × I.D. 2 in. × 0.029 in. × 0.012 in.

22273

Valco® Precision Sampling Syringe, Series A-2, Removable needle

Valco® Precision Sampling Syringe, Series A-2, Removable needle volume 25 μL, bevel tip stainless steel needle (point style 2), needle L × O.D. × I.D. 2 in. × 0.028 in. × 0.005 in.

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Valco® Precision Sampling Syringe, Series A-2, Removable needle

Valco® Precision Sampling Syringe, Series A-2, Removable needle volume 5 mL, bevel tip stainless steel needle (point style 2), needle L × O.D. × I.D. 2 in. × 0.029 in. × 0.012 in.

22275

Valco® Precision Sampling Syringe, Series A-2, Removable needle

packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

packaging

pkg of 1 ea

material

bevel tip stainless steel needle (point style 2)

material

bevel tip stainless steel needle (point style 2)

material

bevel tip stainless steel needle (point style 2)

material

bevel tip stainless steel needle (point style 2)

volume

10 mL

volume

1000 μL

volume

25 μL

volume

5 mL

manufacturer/tradename

VICI 050036

manufacturer/tradename

VICI 050033

manufacturer/tradename

VICI 050023

manufacturer/tradename

VICI 050035

needle size

22 ga

needle size

-

needle size

-

needle size

-

description

Series A-2

description

Series A-2

description

Series A-2

description

Series A-2

General description

CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

  • Bonded phase: Teicoplanin
  • Operating pH range: 3.8 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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    Certificates of Analysis (COA)

    Lot/Batch Number
    275594-01
    275490-01
    268535-01
    266024-01
    258043-01

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    Chromatography Liquid Chiral Separations
    Xiao, T.L., et al.
    Encyclopedia of Separation Science, 1-15 (2000)
    Chromatographic Separations and Analysis: Macrocyclic Glycopeptide Chiral Stationary Phases
    Berthod, A.
    Comprehensive Chirality, 8, 227-262 (2012)
    Ping Sun et al.
    Journal of molecular structure, 890(1-3), 75-80 (2008-11-12)
    A high performance liquid chromatographic method using macrocyclic glycopeptide chiral stationary phases (CSPs) was used to separate enantiomers of seven ruthenium(II) polypyridyl complexes. Among the five different CSPs, the Chirobiotic T2 was most effective and baseline separated all complexes. All
    Chris Hamman et al.
    Journal of chromatography. A, 1305, 310-319 (2013-07-31)
    A rapid screening method to identify the best conditions for chiral separations is described. We analyzed a representative set of 80 racemic compounds against 25 different chiral stationary phases with three different mobile phases to identify the combination of columns
    Sarangan Ravichandran et al.
    Journal of chromatography. A, 1269, 218-225 (2012-08-25)
    The enantioselective separations of the chiral oxazaphosphorines (R,S)-ifosfamide (IF), (R,S)-2-N-dechloroethyl-IF (2-DCE-IF) and (R,S)-3-N-dechloroethyl-IF (3-DCE-IF) were achieved on teicoplanin-based chiral stationary phase using isopropanol:methanol (60:40, v/v) as the mobile phase. Computational models of the teicoplanin and teicoplanin aglycon (TAG) chiral selectors
    View All Related Papers

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