16024AST
Astec® CHIROBIOTIC® T2 Chiral (5 μm) HPLC Columns
L × I.D. 25 cm × 4.6 mm, HPLC Column
Synonym(s):
T2 Chiral Stationary Phase Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Pricing and availability is not currently available.
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Product Name
Astec® CHIROBIOTIC® T2 Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
material
stainless steel column
Quality Level
agency
suitable for USP L63
description
HPLC column
product line
Astec®
packaging
pkg of 1 ea
manufacturer/tradename
Astec®
parameter
0-45 °C temperature
241 bar pressure (3500 psi)
technique(s)
HPLC: suitable
LC/MS: suitable
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1 of 4
This Item | 1.93103 | 1.06733 | 1.04764 |
|---|---|---|---|
| particle size 2-5 mm, coeff var ≥95% | particle size - | particle size 1-2.5 mm | particle size - |
| Quality Level 200 | Quality Level - | Quality Level 200 | Quality Level 200 |
| bulk density 75 g/100 mL | bulk density - | bulk density 750 kg/m3 | bulk density - |
| loss 13.0 - 18.0% loss on drying, (105°C) | loss - | loss - | loss - |
| color , Passes test | color - | color - | color - |
| capacity ≥25 % absorption capacity (CO2)((method NF XVII)) | capacity - | capacity - | capacity - |
General description
CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.
- Bonded phase: Teicoplanin
- Operating pH range: 3.8 - 6.8
- Particle diameter: 5, 10 or 16 μm
- Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)
Application
- High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This research employs the Astec® CHIROBIOTIC T2 Chiral HPLC Column for the enantioseparation of various amino acids. The study highlights the column′s effectiveness in separating complex chiral molecules, demonstrating its application in the analysis of amino acids and related compounds in chemical and pharmaceutical research (Berkecz et al., 2009).
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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