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Ascentis® Express 90 Å AQ-C18, (2 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm UHPLC Column

Synonym(s):

Ascentis® Express 90 Å AQ-C18, 2 μm HPLC Column

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About This Item

UNSPSC Code:
41115700
NACRES:
SB.52

Pricing and availability is not currently available.

Product Name

Ascentis® Express 90 Å AQ-C18, 2.0 μm HPLC Column, column L × I.D. 15 cm × 2.1 mm

material

stainless steel column

agency

suitable for USP L1

product line

Ascentis®

feature

endcapped

packaging

1 ea of

extent of labeling

6.5% Carbon loading

technique(s)

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

column L × I.D.

15 cm × 2.1 mm

surface area

120 m2/g

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1 of 4

This Item
WH0003915M1MAB1924MAB1904
antibody form

ascites fluid

antibody form

purified immunoglobulin

antibody form

ascites fluid

antibody form

purified antibody

biological source

mouse

biological source

mouse

biological source

mouse

biological source

rat

Gene Information

human ... LAMC1(3915)

Gene Information

human ... LAMC1(3915)

Gene Information

human ... LAMA2(3908)

Gene Information

mouse ... Lama1(16772)

clone

2E8, monoclonal

clone

2E6-B4, monoclonal

clone

4C7, monoclonal

clone

AL-2, monoclonal

species reactivity

rat, human

species reactivity

human

species reactivity

human

species reactivity

mouse

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

wet ice

General description

Ascentis® Express AQ-C18 is a high-speed, high-performance liquid chromatography column based on the Fused-Core® particle design. The particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.4 μm thick porous shell and the small overall particle size of 2 μm. The AQ-C18 is a C18 bonded phase prepared using a proprietary procedure that incorporates a small amount of polar silane which makes the phase resistant to dewetting. This resistance to dewetting allows the users of the AQ-C18 phase to run highly-aqueous (up to 100%) mobile phases. The modified C18 phase exhibits similar retention to Ascentis® Express C18 with a different selectivity, adding a valuable alternative for resolving difficult separations. The AQ-C18 is a reversed-phase packing that can be used for basic, acidic, and neutral compounds.

Analysis Note

The target analytes include acids, bases, and polar analytes.

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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Anthony Scott et al.
Acta biochimica et biophysica Sinica, 46(3), 199-203 (2014-01-07)
DNA methylation is an important epigenetic mechanism that ensures correct gene expression and maintains genetic stability. DNA methyltransferase 1 (DNMT1) is the primary enzyme that maintains DNA methylation during replication. Dysregulation of DNMT1 is implicated in a variety of diseases.
Jianqing Lin et al.
The Prostate, 71(4), 333-343 (2010-09-03)
The clinical success of the nucleoside analogs 5-aza-cytidine (5-azaC) and 5-aza-2'deoxycytidine (5-aza-dC) as DNA methyltransferase (DNMT) inhibitors has spurred interest in the development of non-nucleoside inhibitors with improved pharmacologic and safety profiles. Because DNMT catalysis features attack of cytosine bases
Anthony M Chomyk et al.
Scientific reports, 7(1), 8696-8696 (2017-08-20)
Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of the human central nervous system (CNS). Memory impairments and hippocampal demyelination are common features in MS patients. Our previous data have shown that demyelination alters neuronal gene expression in the hippocampus.
Jikui Song et al.
Science (New York, N.Y.), 331(6020), 1036-1040 (2010-12-18)
Maintenance of genomic methylation patterns is mediated primarily by DNA methyltransferase-1 (DNMT1). We have solved structures of mouse and human DNMT1 composed of CXXC, tandem bromo-adjacent homology (BAH1/2), and methyltransferase domains bound to DNA-containing unmethylated CpG sites. The CXXC specifically
Mihika Pradhan et al.
Biochemistry, 47(38), 10000-10009 (2008-08-30)
DNA cytosine methylation is one of the major epigenetic gene silencing marks in the human genome facilitated by DNA methyltransferases. DNA cytosine-5 methyltransferase 1 (DNMT1) performs maintenance methylation in somatic cells. In cancer cells, DNMT1 is responsible for the aberrant

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