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CHUK

conserved helix-loop-helix ubiquitous kinase

Synonyms:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Species:
UniProtKB ID:
Gene ID:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IKKα Antibody, clone 14A231, clone 14A231, Upstate®, from mouse,
Species Reactivity
human, monkey, mouse
Application
western blot
ANTI-CHUK antibody produced in mouse, clone 4D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
ANTI-CHUK antibody produced in mouse, clone 1F8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-IKKα Mouse mAb (14A231), liquid, clone 14A231, Calbiochem®,
Species Reactivity
human, monkey, mouse
Application
Monoclonal Anti-CHUK, (C-terminal) antibody produced in mouse, clone 2G4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

proximity ligation assay

western blot

Proteins

Product Number
Description
Species
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Species
human
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHUK,
Species
human
MISSION® esiRNA, targeting mouse Chuk,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
IKK Substrate Peptide, ,
Species
human