MTOR
mechanistic target of rapamycin (serine/threonine kinase)
Synonyms:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Species:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...More
UniProtKB ID:
Gene ID:
- Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
- Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
- Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
- Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
- cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
- Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
- domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
- dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
- fruit fly(36264) Megator
- chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
- Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
- naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
- domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
- Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
- sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-mTOR Antibody, clone F11, clone F11, from mouse,
Species Reactivity
human, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-mTOR (Thr2446) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-phospho-mTOR (Thr2164) Antibody, serum, from rabbit,
Species Reactivity
human
Application
dot blot
western blot
western blot
Anti-phospho-mTOR (Ser2159) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat, sheep, zebrafish
Application
dot blot
inhibition assay
western blot
inhibition assay
western blot
mTOR phosphorylation Pathway Explorer Antibody MiniPack, This Antibody pack of Anti-mTOR antibodies contains Anti-phospho-mTOR Antibody(Ser2481), Anti-phospho-mTOR Antibody (Thr2446), Anti-phospho-mTOR (Ser2448).,
Species Reactivity
Application
activity assay
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Species
human
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species