콘텐츠로 건너뛰기
Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

동의어:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
종:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...더
UniProtKB ID:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Clone ID:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
설명
종별 반응성
응용분야
09-345
Anti-phospho-mTOR (Thr2446) Antibody, Upstate®, from rabbit,
종별 반응성
human, mouse, rat
응용분야
western blot
ABS88
Anti-phospho-mTOR (Thr2164) Antibody, serum, from rabbit,
종별 반응성
human
응용분야
dot blot
western blot
ABS79
Anti-phospho-mTOR (Ser2159) Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
human, mouse, rat, sheep, zebrafish
응용분야
dot blot
inhibition assay
western blot
SAB4504476
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
SAB4301415
Anti-phospho-mTOR (pThr2446) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot

Small Molecule - Inhibitor

Product Number
설명
종
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
종
human

Proteins

Product Number
설명
종
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
종
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
종
human

esiRNA

Product Number
설명
종
EHU101641
MISSION® esiRNA, targeting human MTOR,
종
human