132179

2,4,6-Trimethylaniline

98%

• Synonym(s): Mesidine
• Linear Formula: (CH₃)₃C₆H₂NH₂
• CAS Number: 88-05-1
• Molecular Weight: 135.21
• Beilstein: 636559
• EC Number: 201-794-3
• MDL number: MFCD00007740
• UNSPSC Code: 12352100
• PubChem Substance ID: 24847550
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.551 (lit.)
• bp: 108-110 °C/11 mmHg (lit.); 233 °C (lit.)
• density: 0.963 g/mL at 25 °C (lit.)
• SMILES string: Cc1cc(C)c(N)c(C)c1
• InChI: 1S/C9H13N/c1-6-4-7(2)9(10)8(3)5-6/h4-5H,10H2,1-3H3
• InChI key: KWVPRPSXBZNOHS-UHFFFAOYSA-N

Description

Application

• Synthesis and crystal structures of N,2,4,6-tetra-methyl-anilinium tri-fluoro-methane-sulfonate and N-iso-propyl-idene-N,2,4,6-tetra-methyl-anilinium tri-fluoro-methane-sulfonate.: This study presents the synthesis and structural analysis of two compounds derived from 2,4,6-Trimethylaniline, contributing to understanding its role in organic synthesis and crystal engineering (Stewart et al., 2024).
• Analysis of aromatic amines in human urine using comprehensive multi-dimensional gas chromatography-mass spectrometry (GCxGC-MS).: This paper explores advanced analytical techniques for detecting aromatic amines, including 2,4,6-Trimethylaniline, demonstrating its relevance in environmental and biological studies (Lorenzo-Parodi et al., 2024).
• Efficient Rhodium-Catalyzed Multicomponent Reaction for the Synthesis of Novel Propargylamines.: This research highlights the use of 2,4,6-Trimethylaniline in developing new catalytic methods, showcasing its importance in pharmaceutical intermediate synthesis (Rubio-Pérez et al., 2015).

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H302 + H312,H315,H319,H330
• Precautionary Statements: P260 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 204.8 °F - closed cup
• Flash Point(C): 96 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves