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927996

Sigma-Aldrich

Gold nanoparticles

100 nm diameter, Ni-NTA functionalized, 1 ML, OD 50, in water

Synonym(s):

AuNP, GdNP, Gold NP

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5 MG
502,00 $

About This Item

UNSPSC Code:
12141717
NACRES:
NA.22

502,00 $

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Quality Level

100

description

Ni-NTA surface density: 1/nm2

concentration

in water

OD

50

core diam.

100 nm , coefficient of variance <12%

diameter

100 nm

λmax

572 nm

PDI

<0.200

functional group

Ni-NTA

storage temp.

2-8°C

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1282730

Fondaparinux sodium System Suitability Mixture B

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1235139

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1620220

Stavudine System Suitability Mixture

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1000829

Abiraterone System Suitability Mixture

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

USP

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

mixture

format

mixture

format

mixture

format

mixture

API family

fondaparinux

API family

emtricitabine

API family

stavudine

API family

abiraterone

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-10 to -25°C

storage temp.

-

General description

Ni-NTA functionalized gold nanoparticles are suitable for binding of proteins with a C-, or N-terminal 6X His tag. These gold nanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays.

Ni-NTA functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Storage and Stability

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Joris W De Schutter et al.
    Bioorganic & medicinal chemistry letters, 20(19), 5781-5786 (2010-08-31)
    A structure-based approach was pursued in designing novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase (hFPPS). Preliminary SAR and structural evidence for the simultaneous binding of these inhibitors into the isopentenyl pyrophosphate (IPP) and the geranyl pyrophosphate (GPP) substrate
    Fu-Lien Hsieh et al.
    Journal of molecular biology, 404(5), 859-873 (2010-10-23)
    Isoprenoids, most of them synthesized by prenyltransferases (PTSs), are a class of important biologically active compounds with diverse functions. The mint geranyl pyrophosphate synthase (GPPS) is a heterotetramer composed of two LSU·SSU (large/small subunit) dimers. In addition to C(10)-GPP, the
    Ken'ichi Hagiwara et al.
    Biochemistry, 43(2), 300-309 (2004-01-14)
    Farnesylation of the gamma-subunit of the retinal G-protein, transducin (Talpha/Tbetagamma), is indispensable for light-initiated signaling in photoreceptor cells. However, the farnesyl-mediated molecular interactions important for signaling are not well understood. To explore this issue, we created a functional Tbetagamma analogue
    J Fraser Glickman et al.
    Assay and drug development technologies, 5(2), 205-214 (2007-05-05)
    A mix-and-read FlashPlate (PerkinElmer, Waltham, MA) assay for the enzyme farnesyl pyrophosphate (FPP) synthase (FPPS) was developed to rapidly measure both steps in the synthesis of FPP from dimethylallyl pyrophosphate (DMAPP). The assay used either DMAPP or geranyl pyrophosphate (GPP)
    Tao-Hsin Chang et al.
    The Plant cell, 22(2), 454-467 (2010-02-09)
    Terpenes (isoprenoids), derived from isoprenyl pyrophosphates, are versatile natural compounds that act as metabolism mediators, plant volatiles, and ecological communicators. Divergent evolution of homomeric prenyltransferases (PTSs) has allowed PTSs to optimize their active-site pockets to achieve catalytic fidelity and diversity.
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