B75956

4-Bromophenylboronic acid

≥95.0%

• Synonym(s): (p-Bromophenyl)boronic acid, 4-Bromobenzeneboronic acid, 4-Bromophenylboric acid, p-Bromobenzeneboronic acid, p-Bromophenylboric acid, NSC 25407
• Linear Formula: BrC₆H₄B(OH)₂
• CAS Number: 5467-74-3
• Molecular Weight: 200.83
• Beilstein: 2936347
• EC Number: 226-779-9
• MDL number: MFCD00002104
• UNSPSC Code: 12352103
• PubChem Substance ID: 24892010
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: ≥95.0%; 95%
• form: crystals
• mp: 284-288 °C (lit.)
• SMILES string: OB(O)c1ccc(Br)cc1
• InChI: 1S/C6H6BBrO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
• InChI key: QBLFZIBJXUQVRF-UHFFFAOYSA-N

Description

Application

Reagent used for

• Palladium catalyzed Suzuki-Miyaura cross-couplings
• Pd(II)-catalyzed diastereoselective conjugate additions
• Palladium-catalyzed stereoselective Heck-type reaction of allylic esters with arylboronic acids
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
• Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides
• Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes
• Copper-catalyzed cross-couplings

Reagent used in Preparation of

• Gallate-based obovatol analogs with potential anti-tumor activity
• Protein modulators and enzymatic and kinase inhibitors

Other Notes

Contains varying amounts of anhydride

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves