12668-M

Albumin, Human Serum, Fraction V

• Synonym(s): Albumin, Human Serum, Fraction V
• CAS Number: 70024-90-7
• MDL number: MFCD00081418
• UNSPSC Code: 12352202

Properties

• description: Merck USA index - 14, 8468
• Assay: ≥95% (SDS-PAGE)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• solubility: water: 20 mg/mL
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N

Description

General description

Human serum albumin (HSA), a globular, soluble, and unglycosylated monomeric protein, is the most abundant protein in the plasma. It is a multidomain protein consisting of three homologous domains, named I, II, and III. Each of these domains contains subdomains A and B possessing common structural motifs. The HSA gene is present on the human chromosome location 4q13.3.

Biochem/physiol Actions

Human serum albumin (HSA) serves as a carrier protein for fatty acids, thyroid hormones, and steroids. It plays a critical role in stabilizing extracellular fluid volume. HSA acts as an excipient for vaccines and therapeutic protein drugs. It is also used as a cell culture medium supplement to produce vaccines and pharmaceuticals. HSA is used to treat hemodialysis, acute liver failure, chronic liver disease. HSA has importance in biological applications, such as ligand trapping, nano delivery of drugs, and fusion proteins.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable