A7736

Albumin human

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

• Synonym(s): Albagen^™, rHSA
• Empirical Formula (Hill Notation): C₂₉₃₆H₄₆₂₄N₇₈₆O₈₈₉S₄₁
• CAS Number: 70024-90-7
• Molecular Weight: 66471.53
• EC Number: 274-272-6
• MDL number: MFCD00081418
• UNSPSC Code: 12352202
• NACRES: NA.25

Properties

• biological source: human
• recombinant: expressed in Pichia pastoris
• Assay: ≥90% (agarose gel electrophoresis)
• form: lyophilized powder
• mol wt: monomer ~67 kDa
• technique(s): cell culture | mammalian: suitable
• UniProt accession no.: P02768
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N
• Gene Information: human ... ALB(213)

Description

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical properties

Construct with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin confirmed x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by eliminating the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Also blocked at Cys³⁴ to improve stability, monomer content and homogeneity.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable