A1312

Alternariol from Alternaria sp.

~96%

• Synonym(s): 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
• Empirical Formula (Hill Notation): C₁₄H₁₀O₅
• CAS Number: 641-38-3
• Molecular Weight: 258.23
• MDL number: MFCD00133068
• UNSPSC Code: 12352200
• PubChem Substance ID: 24890529
• NACRES: NA.77

Properties

• Assay: ~96%
• Quality Level: 200
• form: powder
• storage temp.: 2-8°C
• SMILES string: Cc1cc(O)cc2OC(=O)c3c(O)cc(O)cc3-c12
• InChI: 1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3
• InChI key: CEBXXEKPIIDJHL-UHFFFAOYSA-N

Description

General description

Alternariol belongs to the dibenzo-pyrones chemical group. It is a mycotoxin present in indoor air, soil and plants.

Application

Alternariol from Alternaria sp. may be used as a calibration standard in reverse phase high-performance liquid chromatography (HPLC) and UV-spectrum analysis. It may also be used to spike wholemeal wheat flour for wet baking studies

Biochem/physiol Actions

Alternaria mycotoxins are generally associated with undried food grains post-harvest. The disease caused by Alternaria mycotoxin results in a discolored halo in fruits and spotting in leaves. Alternariol (AOH) is cytotoxic and fetotoxic to microbes and mammalian cells. AOH displays inhibitory effect on cell proliferation and has estrogenic functionality.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330
• Precautionary Statements: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves