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Key Documents

SML2159

Sigma-Aldrich

Minodronic acid monohydrate

≥98% (HPLC)

Synonym(s):

[1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethylidene]bisphosphonic acid monohydrate

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About This Item

Empirical Formula (Hill Notation):
C9H12N2O7P2 · H2O
CAS Number:
Molecular Weight:
340.16
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

0.1 M NaOH: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

OC(P(O)(O)=O)(P(O)(O)=O)CC1=CN=C2N1C=CC=C2.O

InChI

1S/C9H12N2O7P2.H2O/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8;/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18);1H2

InChI key

GPAPAOGRNKUFGH-UHFFFAOYSA-N

Biochem/physiol Actions

Bone resorption inhibitor; inhibitor of farnesyl diphosphate synthase
Minodronate is a third-generation bisphosphonate used clinically alone or in combination to treat osteoporosis. It is an inhibitor of farnesyl diphosphate synthase that acts as a bone resorption inhibitor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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