SML3500

Colesevelam hydrochloride

• Synonym(s): 1-Hexanaminium, N,N,N-trimethyl-6-(2-propenylamino)-, chloride, polymer with (chloromethyl)oxirane, 2-propen-1-amine and N-2-propenyl-1-decanamine, hydrochloride, 2-Propen-1-amine, polymer with (chloromethyl)oxirane, N-2-propenyl-1-decanamine and N,N,N-trimethyl-6-(2-propenylamino)-1-hexanaminium chloride, hydrochloride, CholestaGel, Colesevelam HCl, GT 31-104
• Linear Formula: (C₁₃H₂₇N.C₁₂H₂₇N₂.C₃H₇N.C₃H₅ClO.Cl)x.xHCl
• CAS Number: 182815-44-7
• UNSPSC Code: 12352200
• NACRES: NA.21

Properties

• form: powder
• Quality Level: 100
• mol wt: 581.79 g/mol
• storage condition: desiccated
• color: white to beige
• storage temp.: -10 to -25°C
• SMILES string: C=CCNCCCCCCCCCC.C=CCNCCCCCC[N+](C)(C)C.NCC=C.ClCC1OC1.[xHCl].[Cl-]

Description

Biochem/physiol Actions

Colesevelam hydrochloride, a polyamine polymer, is an oral, non-absorbed bile acid sequestrant. Colesevelam hydrochloride absorbs bile acids in the intestine, which increases demand for cholesterol synthesis and affectively lowers low-density lipoprotein cholesterol (LDL-C) blood levels.

Oral, non-absorbed bile acid sequestrant

Caution

Hygroscopic

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable