157945

(4-Carboxybutyl)triphenylphosphonium bromide

98%

• Synonyme(s) : 5-(Triphenylphosphonio)pentanoic acid bromide, Carboxybutyltriphenylphosphonium bromide, NSC 147756
• Formule linéaire : (C₆H₅)₃P(Br)(CH₂)₄COOH
• CAS Number: 17814-85-6
• Poids moléculaire : 443.31
• Beilstein: 3586477
• Numéro CE : 241-782-5
• Numéro MDL: MFCD00011906
• Code UNSPSC : 12352107
• ID de substance PubChem : 24849711
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Essai: 98%
• Forme: powder
• Capacité de réaction: reaction type: C-C Bond Formation
• Pf: 204-207 °C (lit.)
• Groupe fonctionnel: carboxylic acid; phosphine
• Chaîne SMILES: [Br-].OC(=O)CCCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C23H23O2P.BrH/c24-23(25)18-10-11-19-26(20-12-4-1-5-13-20,21-14-6-2-7-15-21)22-16-8-3-9-17-22;/h1-9,12-17H,10-11,18-19H2;1H
• Clé InChI: MLOSJPZSZWUDSK-UHFFFAOYSA-N

Description

Application

• Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells

Reactant for preparation of:

• Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
• Methyl alkenyl quinolones as antimycobacterial agents
• Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
• Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
• Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
• Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction

Informations sur la sécurité

• Pictogrammes: GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H301,H318
• Conseils de prudence: P264 - P280 - P301 + P310 - P305 + P351 + P338 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral - Eye Dam. 1
• Code de la classe de stockage: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves