349720

(3-Carboxypropyl)triphenylphosphonium bromide

98%

• Synonyme(s) : (4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
• Formule linéaire : HO₂C(CH₂)₃P(C₆H₅)₃Br
• CAS Number: 17857-14-6
• Poids moléculaire : 429.29
• Numéro MDL: MFCD00274196
• Code UNSPSC : 12352002
• ID de substance PubChem : 24861704
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 98%
• Capacité de réaction: reaction type: C-C Bond Formation
• Pf: 244-247 °C (lit.)
• Groupe fonctionnel: carboxylic acid; phosphine
• Chaîne SMILES: [Br-].OC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H
• Clé InChI: NKVJKVMGJABKHV-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity
• Boron-containing benzoxaboroles as antimalarial agents
• Methyl alkenyl quinolones as antimycobacterial agents
• Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-allylation sequence
• Organotin compounds as antifungal agents
• Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity)
• 11-oxa prostaglandin analogs with ocular hypotensive activity

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves