222410

5-Methylindole

99%

• Synonyme(s) : NSC 522562
• Formule empirique (notation de Hill) : C₉H₉N
• CAS Number: 614-96-0
• Poids moléculaire : 131.17
• Numéro CE : 210-400-9
• Numéro MDL: MFCD00005680
• Code UNSPSC : 12352100
• ID de substance PubChem : 24853330
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 99%
• Forme: solid
• Pf: 60-62 °C (lit.)
• Chaîne SMILES: Cc1ccc2[nH]ccc2c1
• InChI: 1S/C9H9N/c1-7-2-3-9-8(6-7)4-5-10-9/h2-6,10H,1H3
• Clé InChI: YPKBCLZFIYBSHK-UHFFFAOYSA-N

Description

Description générale

The binding of 5-methylindole (inducer) to the Escherichia coli trp repressor has been studied. The mass analyzed threshold ionization spectra of jetcooled 5-methylindole (5MI) has also been studied.

Application

Reactant for preparation of:

• Pharmaceutically active 2-oxo-1-pyrrolidine analogues
• Potential anticancer immunomodulators
• Preparation of antifungal agents
• Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes
• IL2-inducible T-cell kinase (ITK) inhibitors
• Checkpoint 1 kinase inhibitors
• CRTh2 antagonists
• Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment
• Agonists of the histamine H4 receptor
• Monoamine reuptake inhibitors

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves