563838

5-Iodoindole

97%

• Formule empirique (notation de Hill) : C₈H₆IN
• CAS Number: 16066-91-4
• Poids moléculaire : 243.04
• Numéro MDL: MFCD00220065
• Code UNSPSC : 12352100
• ID de substance PubChem : 24880134
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Essai: 97%
• Pf: 101-104 °C (lit.)
• Groupe fonctionnel: iodo
• Chaîne SMILES: Ic1ccc2[nH]ccc2c1
• InChI: 1S/C8H6IN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
• Clé InChI: TVQLYTUWUQMGMP-UHFFFAOYSA-N

Description

Description générale

5-Iodoindole can be synthesized via nitration of m-toluidine.

Application

5-Iodoindole (5-iodogramine) may be used in the synthesis of the following:

• 3-dimethylaminomethyl-5-iodoindole via reaction with dimethyl amine and formaldehyde
• 5-ethynyl-1H-indole obtained via refluxing with trimethylsilylacetylene in the presence of triethylamine, catalyzed by palladium and copper(I)iodide in acetonitrile
• 5-(3-hydroxyprop-1-enyl)-1H-indole via reaction with allyl alcohol in the presence of triphenyl phosphine, palladium acetate and silver acetate in dimethylformamide
• 5-(3-benzyloxyprop-1-enyl)-1H-indole via reaction with allylbenzyl ether in the presence of triphenyl phosphine, palladium acetate and silver acetate in dimethylformamide
• 5-(2-phenylethynyl)-1H-indole via refluxing with phenylacetylene catalyzed by copper(I)iodide and palladium in the presence of triethylamine in acetonitrile

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves