700138P

7-dehydrodesmosterol

powder

• Synonyme(s) : Cholesta-5,7,24-trien-3β-ol
• Formule empirique (notation de Hill) : C₂₇H₄₂O
• CAS Number: 1715-86-2
• Poids moléculaire : 382.62
• Numéro MDL: MFCD28359052
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Conditionnement: pkg of 1 × 1 mg (700138P-1mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 700138P
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Chaîne SMILES: O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@@H](CC[C@@H]4[C@@H](CCC=C(C)C)C)C3=CC=C2C1)C)C
• InChI: 1S/C27H42O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,9-10,19,21,23-25,28H,6,8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1
• Clé InChI: RUSSPKPUXDSHNC-DDPQNLDTSA-N

Description

Description générale

7-dehydrodesmosterol (7-DHD) is synthesized via the Bloch pathway. 7-DHD serves as a desmosterol synthesis precursor and the enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes this step.

Application

7-dehydrodesmosterol has been used as an internal oxysterol standard in ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS).

Actions biochimiques/physiologiques

7-dehydrodesmosterol (7-DHD) levels are higher during fetal development and increases with aging. Elevated levels of 7-DHD is associated with Smith-Lemli-Opitz syndrome mouse model. Reduced levels of 7-DHD is observed in shiverer and quaking disorder.

Conditionnement

5 mL Amber Glass Screw Cap Vial (700138P-1mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids