LM1906

17:0-20:4 PI(3,4,5)P3

Avanti Research^™ - A Croda Brand LM1906, powder

• Synonyme(s) : 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt)
• Formule empirique (notation de Hill) : C₄₆H₉₆N₄O₂₂P₄
• CAS Number: 1246304-72-2
• Poids moléculaire : 1181.16
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Forme: powder
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand LM1906
• Conditionnement: 1 ea of 1 × (with stopper and crimp cap (LM1906-1EA))
• Application(s): lipidomics; metabolomics
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@@H](OP(O)([O-])=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
• InChI: 1S/C46H84O22P4.4H3N/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-40(48)64-38(36-62-39(47)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2)37-63-72(60,61)68-43-41(49)44(65-69(51,52)53)46(67-71(57,58)59)45(42(43)50)66-70(54,55)56;;;;/h11,13,17,19,21,23,2
• Clé InChI: FSWQCDGXUXSIRI-VHLOILQVSA-N

Description

Description générale

Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is localized to the plasma membrane, intracellular sites and the nucleus.

Application

17:0-20:4 PI(3,4,5)P3 or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) has been used:

• as a lipid standard in ultra-performance liquid chromatography-tandem mass spectrometry (UPLC/MS)
• as an internal standard in lipid extraction from Drosophila larval tissues
• as an internal standard in liquid chromatography tandem mass spectroscopic (LC-MS/MS) analysis of methylated phosphatidylinositol phosphates (PIPs)

Actions biochimiques/physiologiques

Phosphatidylinositol-3,4,5-triphosphate (PI(3,4,5)P3) is involved in protein activation. It is a critical signaling molecule for several cellular processes and acts as a secondary messenger. PI(3,4,5)P3 is also implicated in human pathogenesis.

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1906-1EA)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids