R7649

(−)-Riboflavine

meets USP testing specifications

• Synonyme(s) : Lactoflavin, Vitamin B₂, Vitamin G
• Formule empirique (notation de Hill) : C₁₇H₂₀N₄O₆
• CAS Number: 83-88-5
• Poids moléculaire : 376.36
• Beilstein: 97825
• Numéro CE : 201-507-1
• Numéro MDL: MFCD00005022
• Code UNSPSC : 12352205
• eCl@ss : 34058005
• ID de substance PubChem : 24899397
• Nomenclature NACRES : NA.21

Propriétés

• Agence: USP/NF; meets USP testing specifications
• Niveau de qualité: 200
• Essai: 98.0-102.0% dry basis
• Forme: powder
• Couleur: dark yellow
• Pf: 290 °C (dec.) (lit.)
• Application(s): pharmaceutical (small molecule)
• Chaîne SMILES: CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1
• InChI: 1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
• Clé InChI: AUNGANRZJHBGPY-SCRDCRAPSA-N

Description

Description générale

Riboflavin is an essential vitamin soluble in water. Milk and eggs are found to be its major sources. Riboflavin is usually bound to enzymes in all tissues. During riboflavin localization in plasma, it is bound to albumin and specific immunoglobulins.

Application

(-)-Riboflavin has been used to study its antimicrobial effect in vitro, through ultraviolet light A (UVA) activation.It has also been used collagen coated surface of the polyethylene membrane for cross-linking astrocytes.

Actions biochimiques/physiologiques

Riboflavin serves as a precursor for the active enzyme cofactors riboflavin 5′-monophosphate (also called flavin mononucleotide or FMN) and flavin adenine dinucleotide (FAD). Riboflavin deficiency in the diet results in a well-defined syndrome known as ariboflavinosis, Riboflavin exhibits protective effects against tumor development and cardiovascular disease. Its deficiency often affects metabolism involving redox reactions. Riboflavin is found essential for iron absorption, gastrointestinal development, neurogenesis, corneal vascularization and corneal opacity.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)