R4500

(−)-Riboflavine

from Eremothecium ashbyii, ≥98%

• Synonyme(s) : Lactoflavin, Vitamin B₂, Vitamin G
• Formule empirique (notation de Hill) : C₁₇H₂₀N₄O₆
• CAS Number: 83-88-5
• Poids moléculaire : 376.36
• Beilstein: 97825
• Numéro CE : 201-507-1
• Numéro MDL: MFCD00005022
• Code UNSPSC : 12352205
• eCl@ss : 34058005
• ID de substance PubChem : 57654591
• Nomenclature NACRES : NA.79

Propriétés

• Source biologique: Eremothecium ashbyii
• Niveau de qualité: 200
• Essai: ≥98%
• Forme: powder
• Couleur: yellow to orange
• Pf: 290 °C (dec.) (lit.)
• Température de stockage: room temp
• Chaîne SMILES: CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1
• InChI: 1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
• Clé InChI: AUNGANRZJHBGPY-SCRDCRAPSA-N

Description

Description générale

Riboflavin belongs to the vitamin-B family and contains a pentose side chain ribitol.

Application

Riboflavin has been used:

• to check the role of riboflavin diet in rats
• as a supplement in HECM-6 medium (hamster embryo culture medium)
• as a supplement in the bacterial basal media

Actions biochimiques/physiologiques

Riboflavin is a key component of the redox cofactors flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) that are used by a wide variety of flavoprotein oxidoreductases, dehydrogenase(s), decarboxylase(s) and electron transporters. Riboflavin is involved in various cellular processes, including β oxidation in lipid metabolism, glucose metabolism, protection from cellular oxidative injury, DNA and RNA metabolism, gluconeogenesis, erythropoiesis and generation of corticosteroids. Riboflavin deficiency causes ariboflavinosis with symptoms such as sore throat, hyperemia, edema of oral and mucous membranes, cheilosis and glossitis.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)