02071

Catalase from Corynebacterium glutamicum

solution, deep brown, ≥500000 U/mL

• CAS Number: 9001-05-2
• Numéro CE : 1.11.1.6 (BRENDA, IUBMB)
• Numéro MDL: MFCD00081483
• Code UNSPSC : 12352204
• Nomenclature NACRES : NA.54

Propriétés

• Source biologique: bacterial (Corynebacterium glutamicum)
• Niveau de qualité: 200
• Forme: solution
• Concentration: ≥500000 U/mL
• Couleur: deep brown
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Chaîne SMILES: O(CC)C(=O)c1ccc(cc1)O
• InChI: 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
• Clé InChI: NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description

Description générale

Catalase is ubiquitously found in animals, plants, fungi, and humans. It is made up of looped polypeptide chains that are arranged as tetramers or dimers and a core, that contains iron or manganese ions. Catalase can be differentiated into two types such as heme-containing (type I), which possesses an iron-porphyrin cofactor and a non-heme-containing (type II), which possesses a dinuclear manganese active site.

Application

Catalase from Corynebacterium glutamicum has been used to identify and characterize purified bacterial peptide (PPBP) produced from Bacillus thuringiensis. It has also been used to study its inhibition by nitric oxide.

Actions biochimiques/physiologiques

Catalase is an antioxidant enzyme that plays a role in alleviating oxidative stress by the removal of hydrogen peroxide to produce oxygen and water. Lower levels of catalase lead to several age-related disorders including hypertension, anemia, vitiligo, Parkinson′s disease, Alzheimer′s disease, schizophrenia, bipolar disorders, diabetes mellitus, and cancer.

Définition de l'unité

1 U corresponds to the amount of enzyme which decomposes 1 μmol H₂O₂ per minute at pH 7.0 and 25°C

Forme physique

contains ~30% glycerol, 10% ethanol

Autres remarques

The purity of this product is not determined. It is tested and sold by activity rather than mass.

Informations sur la sécurité

• Pictogrammes: GHS02
• Mention d'avertissement: Warning
• Mentions de danger: H226
• Conseils de prudence: P210 - P233 - P240 - P241 - P242 - P243
• Classification des risques: Flam. Liq. 3
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 105.8 °F - closed cup
• Point d'éclair (°C): 41 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter