A0637

DL-2-Aminoadipic acid

≥99% (TLC), powder, gliotoxic

• Synonyme(s) : DL-α-Aminoadipic acid
• Formule linéaire : HO₂C(CH₂)₃CH(NH₂)CO₂H
• CAS Number: 542-32-5
• Poids moléculaire : 161.16
• Numéro CE : 208-809-2
• Numéro MDL: MFCD00063119
• Code UNSPSC : 12352106
• ID de substance PubChem : 24890441
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: DL-2-Aminoadipic acid, ≥99%
• Niveau de qualité: 200
• Essai: ≥99%
• Forme: powder
• Pf: 196-198 °C (lit.)
• Température de stockage: 2-8°C
• Chaîne SMILES: NC(CCCC(O)=O)C(O)=O
• InChI: 1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)
• Clé InChI: OYIFNHCXNCRBQI-UHFFFAOYSA-N
• Informations sur le gène: rat ... Grin2b(24410)

Description

Application

DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity.

Actions biochimiques/physiologiques

DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H317
• Conseils de prudence: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classification des risques: Skin Sens. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable