A3737

Cefepime hydrochloride

• Synonyme(s) : Cefepime dihydrochloride monohydrate
• Formule linéaire : C₁₉H₂₅N₆O₅S₂Cl · HCl · H₂O
• CAS Number: 123171-59-5
• Poids moléculaire : 571.50
• Numéro MDL: MFCD01687679
• Code UNSPSC : 51282610
• Nomenclature NACRES : NA.85

Propriétés

• Forme: powder
• Niveau de qualité: 200
• Couleur: white to faint yellow
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Mode d’action: cell wall synthesis | interferes
• Température de stockage: −20°C
• Chaîne SMILES: [s]1c(nc(c1)\C(=N\OC)\C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C[N+]4(CCCC4)C)N.[Cl-].[Cl-].O.[H+]
• InChI: 1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
• Clé InChI: LRAJHPGSGBRUJN-OMIVUECESA-N

Description

Description générale

Cefepime is a semi-synthetic fourth-generation cephalosporin. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.

Application

Cefepime was used in antimicrobial susceptibility testing for Acinetobacter baumannii and extended-spectrum-β-lactamase-producing Escherichia coli isolated from various samples.

Actions biochimiques/physiologiques

Cefepime is a broad-spectrum cephalosporin with activity against Gram-positive and Gram-negative bacteria. It binds to penicillin-binding proteins and disrupts the cell wall synthesis.

Autres remarques

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable