D6000

2′-Deoxyadenosine 5′-di­phos­phate sodium salt

• Synonyme(s) : dADP
• Formule empirique (notation de Hill) : C₁₀H₁₅N₅O₉P₂ · xNa⁺
• CAS Number: 72003-83-9
• Poids moléculaire : 411.20 (free acid basis)
• Numéro CE : 276-280-5
• Numéro MDL: MFCD00083610
• Code UNSPSC : 41106305
• ID de substance PubChem : 24893990
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: synthetic (organic)
• Niveau de qualité: 200
• Essai: ≥95% (HPLC)
• Forme: powder
• Température de stockage: −20°C
• Chaîne SMILES: [Na].Nc1ncnc2n(cnc12)C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3
• InChI: 1S/C10H15N5O9P2.Na.H/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19);;
• Clé InChI: KZGAPWRJMWSNQO-UHFFFAOYSA-N

Description

Description générale

2′-Deoxyadenosine5′-di­phos­phate (dADP) is a purine containing adenine as the nucleobase. It isproduced as a product of hypoxanthine oxidase action on hypoxanthine duringpurine degradation in the body.

Application

2′-Deoxyadenosine 5′-diphosphate (dADP) may be used for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. dADP is used as an inhibitor of bacterial poly(A) polymerase. DeoxyADP may be use as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301 + H311 + H331,H315,H319,H335
• Conseils de prudence: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges