I7634

D-Isoleucine

≥98% (TLC)

• Synonyme(s) : (2R, 3R)-2-Amino-3-methylpentanoic acid
• Formule linéaire : C₂H₅CH(CH₃)CH(NH₂)CO₂H
• CAS Number: 319-78-8
• Poids moléculaire : 131.17
• Numéro CE : 206-269-2
• Numéro MDL: MFCD00064221
• Code UNSPSC : 12352209
• ID de substance PubChem : 24896122
• Nomenclature NACRES : NA.26

Propriétés

• Product Name: D-Isoleucine, ≥98% (TLC)
• Niveau de qualité: 200
• Essai: ≥98% (TLC)
• Forme: powder
• Impuretés: ≤10% allo-isomer
• Couleur: white
• Application(s): cell analysis
• Chaîne SMILES: CC[C@@H](C)[C@@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m1/s1
• Clé InChI: AGPKZVBTJJNPAG-RFZPGFLSSA-N

Description

Application

• Metabolic Profiling of Urinary Chiral Amino-Containing Biomarkers for Gastric Cancer Using a Sensitive Chiral Chlorine-Labeled Probe by HPLC-MS/MS.: This study by Huang et al. (2021) explores the use of D-Isoleucine as a biomarker for gastric cancer, utilizing advanced metabolic profiling techniques with HPLC-MS/MS to detect chiral amino-containing compounds in urine samples (Huang et al., 2021).


• Isopenicillin N Synthase Binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine Through Both Sulfur Atoms.: Clifton et al. (2011) describe the binding mechanism of Isopenicillin N synthase with a compound involving D-Isoleucine, highlighting its role in antibiotic biosynthesis and enzyme interaction studies (Clifton et al., 2011).


• The Total Structure of the Antibiotic Longicatenamycin.: Shiba and Mukunoki (1975) determined the complete structure of the antibiotic longicatenamycin, which includes D-Isoleucine as a crucial component, contributing to understanding its antibacterial properties (Shiba and Mukunoki, 1975).

Actions biochimiques/physiologiques

D-Isoleucine may be used to help characterize and differentiate various D-amino acid oxidases. D-Isoleucine may be used to differentiate the activities of D- and L-isoleucine in processes such as the induction of pigmentation in B16F0 melanoma cells.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable