G1001

D-Glutamic acid

≥99% (TLC), suitable for ligand binding assays

• Synonyme(s) : (R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid
• Formule linéaire : HO₂CCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 6893-26-1
• Poids moléculaire : 147.13
• Beilstein: 1723800
• Numéro CE : 230-000-8
• Numéro MDL: MFCD00063112
• Code UNSPSC : 12352209
• ID de substance PubChem : 24895031
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: D-Glutamic acid, ≥99% (TLC)
• Niveau de qualité: 200
• Essai: ≥99% (TLC)
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Couleur: white to off-white
• Pf: 200-202 °C (subl.) (lit.)
• Chaîne SMILES: N[C@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
• Clé InChI: WHUUTDBJXJRKMK-GSVOUGTGSA-N
• Informations sur le gène: human ... CCR2(1231)

Description

Description générale

D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.

Application

D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.

Actions biochimiques/physiologiques

Unnatural isomer of glutamic acid.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)