M4008

Morin hydrate

powder

• Synonyme(s) : 2′,3,4′,5,7-Pentahydroxyflavone
• Formule empirique (notation de Hill) : C₁₅H₁₀O₇ · xH₂O
• CAS Number: 654055-01-3
• Poids moléculaire : 302.24 (anhydrous basis)
• Numéro CE : 207-542-9
• Numéro MDL: MFCD00217054
• Code UNSPSC : 12171500
• ID de substance PubChem : 24278552
• Nomenclature NACRES : NA.77

Propriétés

• Forme: powder
• Niveau de qualité: 100
• Couleur: yellow
• Solubilité: methanol: 50 mg/mL
• Chaîne SMILES: O.Oc1ccc(c(O)c1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C15H10O7.H2O/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15;/h1-5,16-19,21H;1H2
• Clé InChI: MYUBTSPIIFYCIU-UHFFFAOYSA-N

Description

Application

Morin hydrate has been used:

• to investigate its antitumor functionality using cell viability and apoptosis assay in human cancer cell lines.
• as a fluorescence stain to detect aluminum in motor neurons and lumbar cord.
• to study its protective effect on neuronal hearing loss and on neural stem cells (NSCs) proliferation and differentiation

Actions biochimiques/physiologiques

Morin hydrate is a flavonoid with antioxidant properties. It has been shown to protect cells against oxygen radical damage. Morin not only scavenges oxyradicals, but also moderately inhibits xanthine oxidase, a free-radical generating enzyme. At concentrations of 75-100 micromolar, morin inhibits oxidation of low density lipoprotein (LDL) by free radicals or Cu²⁺. Morin has been reported to inhibit rat brain phospha­tidyl­inositol­phos­phate kinase activity in vitro and in vivo.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves