M7439

Méthyl-β-cyclodextrine

• Synonyme(s) : Methyl-beta-cyclodextrin
• CAS Number: 128446-36-6
• Code UNSPSC : 12352201
• Nomenclature NACRES : NA.22

Propriétés

• Forme: powder
• Niveau de qualité: 200
• Impuretés: <10.0% water (Karl Fischer)
• Couleur: white
• Pf: 180-182 °C (lit.)
• Chaîne SMILES: O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC
• InChI: 1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3
• Clé InChI: QGKBSGBYSPTPKJ-UHFFFAOYSA-N

Description

Description générale

Methyl-β-cyclodextrin is a small cyclic heptasaccharide.

Application

Methyl-β-cyclodextrin has been used as a cholesterol chelator:

• to study its effects on mice cardiomyocytes
• to study its effects on human corneal stromal fibroblasts
• to study its effects on the junctophilin-2 (JPH2) pool

Actions biochimiques/physiologiques

Methyl-β-cyclodextrin participates in increasing the permeability of cells. It also plays a role in depolymerizing the actin cytoskeleton in cells. Methyl-β-cyclodextrin is involved in attracting cholesterol from the plasma. It participates in activating extracellular receptor kinase in certain cells.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): 368.6 °F
• Point d'éclair (°C): 187 °C
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)