M7898

Monoclonal Anti-Thy 1.1 antibody produced in mouse

clone TN-26, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : Anti-CD90, Anti-CDw90
• Numéro MDL: MFCD00164701
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: TN-26, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: mouse
• Technique(s): complement-mediated cytotoxicity assay: suitable; indirect immunofluorescence: suitable
• Isotype: IgM
• Numéro d'accès UniProt: P01831
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: mouse ... Thy1(21838)

Description

Description générale

Monoclonal Anti-Thy 1.1 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Thymus cell antigen 1 (Thy 1.1) is a glycosylphosphatidyl-anchored protein. It belongs to the of the immunoglobulin superfamily. Thy 1.1 is expressed in stem cells, T-cells and neurons.

Spécificité

Recognizes Thy 1.1 bearing cells and is less than 5% cross-reactive with Thy 1.2 bearing cells. Titer is 1:20,000 as determined by in vitro cytotoxicity against AKR/J thymocytes.

Immunogène

thymocytes from AKR/J (Thy 1.1) mice.

Application

Monoclonal Anti-Thy 1.1 antibody produced in mouse has been used in immunopanning and immunofluorescence.

Actions biochimiques/physiologiques

Studies have shown that mice lacking the protein thymus cell antigen 1 (Thy 1.1) have an increased number of fibroblasts. It suppresses proliferation and enhances apoptosis in dermal fibroblasts, thereby modulating cell growth. This is carried out by regulating the action of β3 integrin.

Forme physique

Solution in 0.1 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable