N3501

β-Nicotinamide mononucleotide

≥95% (HPLC)

• Synonyme(s) : β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate
• Formule empirique (notation de Hill) : C₁₁H₁₅N₂O₈P
• CAS Number: 1094-61-7
• Poids moléculaire : 334.22
• Beilstein: 3570187
• Numéro CE : 214-136-5
• Numéro MDL: MFCD00038748
• Code UNSPSC : 41106305
• ID de substance PubChem : 24897645
• Nomenclature NACRES : NA.51

Propriétés

• Niveau de qualité: 200
• Essai: ≥95% (HPLC); ≥95% (spectrophotometric assay)
• Forme: powder
• Solubilité: H₂O: soluble-50 mg/mL to clear, colorless to faintly yellow
• Température de stockage: −20°C
• Chaîne SMILES: C[C@H]1[C@@H](C)[C@@H](O[C@@H]1COP(O)([O-])=O)[n+]2cccc(c2)C(N)=O
• InChI: 1S/C13H19N2O6P/c1-8-9(2)13(21-11(8)7-20-22(17,18)19)15-5-3-4-10(6-15)12(14)16/h3-6,8-9,11,13H,7H2,1-2H3,(H3-,14,16,17,18,19)/t8-,9+,11+,13+/m0/s1
• Clé InChI: YYNOOWWEYJELSF-SEMCEJNYSA-N

Description

Description générale

β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

Application

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Autres remarques

Note: This is the common form of NMN. Do not confuse it with α-NMN.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)