O0383

N-Oleoylethanolamine

~98% (TLC)

• Synonyme(s) : N-(Hydroxyethyl)oleamide, N-(cis-9-Octadecenoyl)ethanolamine, OEA, oleoylethanolamide
• Formule empirique (notation de Hill) : C₂₀H₃₉NO₂
• CAS Number: 111-58-0
• Poids moléculaire : 325.53
• Numéro CE : 203-884-8
• Numéro MDL: MFCD00045972
• Code UNSPSC : 12352204
• ID de substance PubChem : 24278603
• Nomenclature NACRES : NA.83

Propriétés

• Essai: ~98% (TLC)
• Niveau de qualité: 200
• Forme: powder
• Solubilité: chloroform: 20 mg/mL, clear, colorless
• Température de stockage: −20°C
• Chaîne SMILES: O=C(CCCCCCC/C=C\CCCCCCCC)NCCO
• InChI: 1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
• Clé InChI: BOWVQLFMWHZBEF-KTKRTIGZSA-N
• Informations sur le gène: human ... CNR1(1268), CNR2(1269), PPARA(5465), TRPV1(7442) ; mouse ... Cnr2(12802) ; rat ... Cnr1(25248)

Description

Description générale

Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine. Small intestine cells, adipose tissues, neurons and astrocytes produces OEA.

Application

N-Oleoylethanolamine has been used to study its effects on glucagon-like peptide (GLP)-1RA-mediated anorectic signaling and weight loss.

Actions biochimiques/physiologiques

Oleoylethanolamide (OEA) is a lipid mediator, which helps to control various biological functions, like food intake. It modulates the gene expression in the small intestine. OEA has the ability to initiate several receptors, such as cannabinoid receptor type 1 (CB1), peroxisome proliferator-activated receptors (PPARs) and G protein-coupled receptor 119 (GPR119).

Peroxisome proliferator-activator receptor α (PPARα) agonist

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves