P0359

Palmitoylethanolamide

≥98% (HPLC), powder, cannabinoid receptor agonist

• Synonyme(s) : N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
• Formule empirique (notation de Hill) : C₁₈H₃₇NO₂
• CAS Number: 544-31-0
• Poids moléculaire : 299.49
• Numéro CE : 208-867-9
• Numéro MDL: MFCD00020562
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278619
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: Palmitoylethanolamide,
• Forme: powder
• Niveau de qualité: 200
• Température de stockage: −20°C
• Chaîne SMILES: CCCCCCCCCCCCCCCC(=O)NCCO
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
• Clé InChI: HXYVTAGFYLMHSO-UHFFFAOYSA-N
• Informations sur le gène: human ... CNR1(1268), CNR2(1269) ; rat ... Faah(29347)

Description

Application

Palmitoylethanolamide has been used as a reference standard in mass spectrometry (MS/MS).

Actions biochimiques/physiologiques

Palmitoylethanolamide (PEA) is a natural fatty acid amide of ethanolamine and palmitic acid. It is found in soybeans, egg yolk, and many other food sources. PEA is an endogenous cannabinoid receptor agonist. It is a peroxisome proliferator-activated receptor α (PPAR-α) ligand. PEA possesses anti-inflammatory, anti-allergic, neuroprotective, and analgesic activities. It belongs to the class of lipid mediators and the N-acylethanolamine family. PEA blocks the release of pro-inflammatory mediators from activated mast cells and prevents the recruitment of activated mast cells at the site of nerve injury.

Liaison

Structural analog of anandamide.

Informations sur la sécurité

• Pictogrammes: GHS05,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H315,H318,H411
• Conseils de prudence: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Classification des risques: Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)