P5556

Poloxamer 188 solution

10%, sterile-filtered, BioReagent, suitable for insect cell culture

• Synonyme(s) : Nonionic copolymer surfactant
• CAS Number: 9003-11-6
• Numéro MDL: MFCD00082049
• Code UNSPSC : 12161902
• ID de substance PubChem : 24898666
• Nomenclature NACRES : NA.75

Propriétés

• Description: non-ionic
• Niveau de qualité: 400
• Stérilité: sterile-filtered
• Gamme de produits: BioReagent
• Poids mol.: average mol wt 8350
• Concentration: 10%
• Technique(s): cell culture | insect: suitable
• Impuretés: endotoxin, tested
• Température de transition: cloud point ≥100
• HLB: 29
• Chaîne SMILES: O2C(C2)C.O1CC1
• InChI: 1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
• Clé InChI: RVGRUAULSDPKGF-UHFFFAOYSA-N

Description

Description générale

Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.

Application

A nonionic copolymer surfactant

Actions biochimiques/physiologiques

Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence. P-188 exhibits low toxicity and may be used in oral drug delivery.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)