P8692

Paromomycin sulfate salt

powder, suitable for plant cell culture, BioReagent

• Formule empirique (notation de Hill) : C₂₃H₄₅N₅O₁₄ · xH₂SO₄
• CAS Number: 1263-89-4
• Poids moléculaire : 615.63 (free base basis)
• Beilstein: 5715182
• Code UNSPSC : 10171502
• ID de substance PubChem : 24898967
• Nomenclature NACRES : NA.72

Propriétés

• Product Name: Paromomycin sulfate salt, suitable for plant cell culture, BioReagent
• Gamme de produits: BioReagent
• Niveau de qualité: 200
• Forme: powder
• Technique(s): cell culture | plant: suitable
• Spectre d'activité de l'antibiotique: Gram-negative bacteria; Gram-positive bacteria
• Application(s): agriculture
• Mode d’action: protein synthesis | interferes
• Chaîne SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O[C@@]2([H])[C@H](O[C@@]3([H])[C@H](O)[C@H](O[C@]4([H])[C@H](N)[C@@H](O)[C@H](O)[C@H](CN)O4)[C@@H](CO)O3)[C@@H](O)[C@H](N)C[C@@H]2N)[C@@H]1N.C
• InChI: 1S/C23H45N5O14.CH4/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;/h5-23,29-36H,1-4,24-28H2;1H4/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1
• Clé InChI: OYJABWUHUYVDMJ-UDXJMMFXSA-N

Description

Description générale

Chemical structure: aminoglycoside

Application

Paromomycin, monomycin, is an aminoglycoside antibiotic used to select genetically transformed plants and plant cells.

Actions biochimiques/physiologiques

Antimicrobial spectrum: Gram-negative and Gram-positive bacteria, some protozoan species, and limited antihelminth.
Mode of Action: Inhibits initiation and elongation during protein synthesis.

Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

Conditionnement

5g,25g

Autres remarques

Keep container tightly closed in a dry and well-ventilated place

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable