S5375

Shikimic acid

≥99%, suitable for ligand binding assays

• Synonyme(s) : (3R,4S,5R)-(−)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid
• Formule empirique (notation de Hill) : C₇H₁₀O₅
• CAS Number: 138-59-0
• Poids moléculaire : 174.15
• Beilstein: 2210055
• Numéro CE : 205-334-2
• Numéro MDL: MFCD00066278
• Code UNSPSC : 12352106
• ID de substance PubChem : 24899647
• Nomenclature NACRES : NA.25

Propriétés

• Product Name: Shikimic acid, ≥99%
• Niveau de qualité: 200
• Essai: ≥99%
• Forme: powder
• Technique(s): ligand binding assay: suitable
• Couleur: white to off-white
• Pf: 185-187 °C (lit.)
• Chaîne SMILES: O[C@@H]1CC(=C[C@@H](O)[C@H]1O)C(O)=O
• InChI: 1S/C7H10O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1,4-6,8-10H,2H2,(H,11,12)/t4-,5-,6-/m1/s1
• Clé InChI: JXOHGGNKMLTUBP-HSUXUTPPSA-N

Description

Application

Shikimic acid has been used as a standard for the quantification of shikimate in apical parts of roots. It has also been used as a substrate in shikimate kinase assay.

Actions biochimiques/physiologiques

Shikimic acid is observed to be carcinogenic in rat models, when administered. It serves as a precursor for the biosynthesis of aromatic amino acids, alkaloids and other aromatic metabolites in microorganisms. Shikimic acid is known to inhibit adenosine diphosphate (ADP) induced platelet aggregation and blood coagulation in rabbits.

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)