SCP0224

Prostate Specific Antigen Substrate

≥95% (HPLC), lyophilized

• Synonyme(s) : KLK3, Kallikrein-related peptidase-3, PSA
• Formule empirique (notation de Hill) : C₄₄H₆₄N₁₂O₁₃
• Poids moléculaire : 969.05
• Code UNSPSC : 12352204
• Nomenclature NACRES : NA.32

Propriétés

• Product Name: Prostate Specific Antigen Substrate,
• Essai: ≥95% (HPLC)
• Forme: lyophilized
• Composition: Peptide Content, ≥75%
• Conditions de stockage: protect from light
• Température de stockage: −20°C

Description

Amino Acid Sequence

Mu-His-Ser-Ser-Lys-Leu-Gln-AMC

Description générale

Prostate specific antigen (PSA) is a kallikrein-related serine peptidase that belongs to the chymotrypsin subfamily serine protease. It was originally found in human semen. PSA is also detected in serum correlated to benign and metastatic disease.

Application

Prostate Specific Antigen Substrate has been used to assay recombinant severe acute respiratory syndrome coronavirus-2 viral 3-chymotrypsin-like cysteine protease (SARS-CoV-2 3CLpro).

Actions biochimiques/physiologiques

Prostate specific antigen (PSA). It exhibits chymotrypsin-like activity. PSA is the most abundant protease found in the prostate and secreted into the seminal fluid. It is a useful biomarker for prostate cancer. PSA digests the gel-forming proteins semenogelins I and II in semen. It shows antiangiogenic activity in vitro and in vivo.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable