SML0041

Batimastat

≥98% (HPLC), powder, matrix metalloproteinase inhibitor

• Synonyme(s) : BB-94; (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide
• Formule empirique (notation de Hill) : C₂₃H₃₁N₃O₄S₂
• CAS Number: 130370-60-4
• Poids moléculaire : 477.64
• Numéro MDL: MFCD00866533
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825111
• Nomenclature NACRES : NA.77

Propriétés

• Product Name: Batimastat, ≥98% (HPLC)
• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to tan
• Solubilité: DMSO: ≥15 mg/mL
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Chaîne SMILES: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc2cccs2)C(=O)NO
• InChI: 1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1
• Clé InChI: XFILPEOLDIKJHX-QYZOEREBSA-N

Description

Application

Batimastat has been used to inhibit matrix metalloproteinases (MMPs) activity in various studies.

Actions biochimiques/physiologiques

Batimastat is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.

Batimastat is hydroxamate-type inhibitor of matrix metalloproteinases (MMP). It inhibits the growth and spread of lung tumors, breast cancer regrowth and human colon tumor growth and spread in mouse models. Batimastat reduces MMP-mediated vascular dysfunction and vessel wall damage and enhances the sealing ability and bond strength of dental adhesives.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable