SML0235

CDPPB

≥98% (HPLC)

• Synonyme(s) : 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide
• Formule empirique (notation de Hill) : C₂₃H₁₆N₄O
• CAS Number: 781652-57-1
• Poids moléculaire : 364.40
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825248
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: DMSO: ≥5 mg/mL at warmed to 60 °C
• Température de stockage: 2-8°C
• Chaîne SMILES: O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N
• InChI: 1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2
• Clé InChI: GZHZEGYXLNXEBV-UHFFFAOYSA-N

Description

Application

CDPPB may be used in mGluR5-mediated cell signaling studies.

Actions biochimiques/physiologiques

Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.

CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.

CDPPB is an mGluR5 positive allosteric modulator

Caractéristiques et avantages

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable