SML0909

Nefopam hydrochloride

≥98% (HPLC)

• Synonyme(s) : 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride, 5-Methyl-1-phenyl-1,3,4,6-tetrahydro-5H-benz[f]-2,5-oxazocine hydrochloride
• Formule empirique (notation de Hill) : C₁₇H₁₉NO · HCl
• CAS Number: 23327-57-3
• Poids moléculaire : 289.80
• Numéro CE : 245-585-5
• Numéro MDL: MFCD00012750
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825616
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white to beige
• Pf: 260 °C (dec.) (lit.)
• Solubilité: H₂O: 5 mg/mL, clear
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.CN1CCOC(c2ccccc2)c3ccccc3C1
• InChI: 1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
• Clé InChI: CNNVSINJDJNHQK-UHFFFAOYSA-N

Description

Application

Nefopam hydrochloride has been used as a standard for the quantitative determination of tramadol by gas chromatography–mass spectrometry (GC/MS).

Actions biochimiques/physiologiques

Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor.

Nefopam is a centrally-acting non-opioid analgesic drug of the benzoxazocine chemical class.

Caractéristiques et avantages

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Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301 + H311 + H331
• Conseils de prudence: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable