SML1537

Cantharidin Ready Made Solution

0.1 mg/mL in DMSO

• Synonyme(s) : 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Formule empirique (notation de Hill) : C₁₀H₁₂O₄
• CAS Number: 56-25-7
• Poids moléculaire : 196.20
• Numéro CE : 200-664-3
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: insect
• Niveau de qualité: 200
• Forme: solution
• Concentration: 0.1 mg/mL in DMSO
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
• InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
• Clé InChI: DHZBEENLJMYSHQ-XCVPVQRUSA-N

Description

Actions biochimiques/physiologiques

Cantharidin inhibits protein phosphatase 2A.

It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.

Autres remarques

Stable for at least two years at 2-8° C.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 188.6 °F
• Point d'éclair (°C): 87 °C