SML1707

Temoporfin

≥90% (HPLC)

• Synonyme(s) : 3,3′,3′′,3′′′-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin
• Formule empirique (notation de Hill) : C₄₄H₃₂N₄O₄
• CAS Number: 122341-38-2
• Poids moléculaire : 680.75
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥90% (HPLC)
• Forme: powder
• Couleur: dark brown to black
• Solubilité: DMSO: 2 mg/mL, clear (warmed)
• Température de stockage: −20°C
• InChI: 1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2
• Clé InChI: LYPFDBRUNKHDGX-UHFFFAOYSA-N

Description

Description générale

Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.

Actions biochimiques/physiologiques

Temoporfin is a photosensitizer for the photodynamic therapy.

Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable