SML1924

T1AM

≥98% (HPLC)

• Synonyme(s) : 3-Iodothyronamine hydrochloride, 4-[4-(2-Aminoethyl)-2-?iodophenoxy]phenol hydrochloride (1:1)
• Formule empirique (notation de Hill) : C₁₄H₁₄INO₂ · HCl
• CAS Number: 788824-64-6
• Poids moléculaire : 391.63
• Numéro MDL: MFCD11973725
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: 10 mg/mL, clear
• Température de stockage: 2-8°C
• Chaîne SMILES: OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl
• InChI: 1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H
• Clé InChI: RVKVVMXTPQCCIX-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

3-iodothyronamine (T1AM) is present in vertebrate tissues and the circulatory system. Its physiological effects are the opposite of the thyroid hormone. T1AM acts as a neuromodulator as well as a hormone-like molecule.

T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone.

T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. T1AM is a potent agonist of trace amine-associated receptor TAAR1 (TAR1, TA1), a GPCR primarily found in the brain.

Informations sur la sécurité

• Pictogrammes: GHS07,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319,H335,H410
• Conseils de prudence: P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3