V3640

Valpromide

≥97% (NMR)

• Synonyme(s) : 2-Propylvaleramide, 2-propyl-pentanamide, Depamid, Depamide, Di-n-propylacetamide, Dipropylacetamide
• Formule empirique (notation de Hill) : C₈H₁₇NO
• CAS Number: 2430-27-5
• Poids moléculaire : 143.23
• Numéro MDL: MFCD00051534
• Code UNSPSC : 12352200
• ID de substance PubChem : 329829044
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥97% (NMR)
• Forme: powder
• Couleur: white to off-white
• Solubilité: DMSO: >10 mg/mL
• Auteur: Sanofi Aventis
• Température de stockage: room temp
• Chaîne SMILES: CCCC(CCC)C(N)=O
• InChI: 1S/C8H17NO/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H2,9,10)
• Clé InChI: OMOMUFTZPTXCHP-UHFFFAOYSA-N

Description

Application

Valpromide has been used to pretreat NIH/3T3 cells to test its effect on cytomegalovirus (CMV) viral replication. It has also been used to test its antiviral functionality in herpes simplex virus type 1 (HSV-1) infected human oligodendroglioma (HOG) cells. It may be used to test its effect on apoptosis induction in astrocytes.

Actions biochimiques/physiologiques

Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug.

Valpromide (VPD) is a derivative of valproic acid (VPA) and is used as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity.

Valpromide possesses antipsychotic property. It lacks the toxic and teratogenic effects of valproic acid. It also lacks the histone deacetylase (HDAC) inhibitory activity of valproic acid.

Caractéristiques et avantages

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable