W108

WAY-100635 maleate salt

powder

• Synonyme(s) : N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate salt
• Formule empirique (notation de Hill) : C₂₅H₃₄N₄O₂ · C₄H₄O₄
• CAS Number: 634908-75-1
• Poids moléculaire : 538.64
• Numéro MDL: MFCD01321056
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278113
• Nomenclature NACRES : NA.77

Propriétés

• Forme: powder
• Niveau de qualité: 100
• Couleur: white
• Solubilité: H₂O: 25 mg/mL
• Chaîne SMILES: [H]\C(=C(/[H])C(O)=O)C(O)=O.COc1ccccc1N2CCN(CC2)CCN(C(=O)C3CCCCC3)c4ccccn4
• InChI: 1S/C25H34N4O2.C4H4O4/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21;5-3(6)1-2-4(7)8/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• Clé InChI: XIGAHNVCEFUYOV-BTJKTKAUSA-N
• Informations sur le gène: human ... HTR1A(3350)

Description

Application

WAY-100635 maleate salt has been used as a 5-HT1A serotonin receptor antagonist:

• to study whether the behavior of the cleaner wrasse is regulated by serotonin activity
• to block activity of 3,4 methylenedioxymethamphetamine (MDMA) used to induce oxytocin release in male Wistar rats to increase their social behavior
• to study the role of serotonin during metamorphosis of the ascidian Phallusia mammillata larvae

Actions biochimiques/physiologiques

WAY-100635 maleate salt is a highly selective 5-HT1A serotonin receptor antagonist. It has an ability to inhibit brexpiprazole, an antipsychotic drug that regulates serotonin-dopamine activity.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)